This newer oral tablet is approved for the treatment of migraine with or without aura. People with coronary artery disease, high blood pressure, or kidney or liver disease should avoid dihydroergotamine. Side effects can include worsening of migraine-related vomiting and nausea. Available as a nasal spray or injection, this drug is most effective when taken shortly after the start of migraine symptoms for migraines that tend to last longer than 24 hours. They might not be safe for those at risk of a stroke or heart attack.ĭihydroergotamine (D.H.E. Taken as pills, shots or nasal sprays, they can relieve many symptoms of migraine. Prescription drugs such as sumatriptan (Imitrex, Tosymra) and rizatriptan (Maxalt, Maxalt-MLT) are used to treat migraine because they block pain pathways in the brain. Migraine relief medications that combine caffeine, aspirin and acetaminophen (Excedrin Migraine) may be helpful, but usually only against mild migraine pain. When taken too frequently, these might cause medication-overuse headaches, and possibly ulcers and bleeding in the gastrointestinal tract. These over-the-counter or prescription pain relievers include aspirin or ibuprofen (Advil, Motrin IB, others). Depending on how severe your migraine pain is, types of medications that can be used to treat it include: Medications used to relieve migraine pain work best when taken at the first sign of an oncoming migraine - as soon as signs and symptoms of a migraine aura begin. For migraine with aura, just as with migraine alone, treatment is aimed at relieving migraine pain.

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